HVMN Ketone - The world's first and only ketone ester

@nivo0o0 of course ! Come on over to our HQ. Let’s test both your blood glucose and blood ketone levels before and after to see how HVMN Ketone immediately affects those 2 biomarkers

@nivo0o0 @geoffreywoo Booking a flight right now!

@geoffreywoo What is the benefit of an ester vs salts?

@kkdub Ketone salts elevate ketones to about 0.3 - 1 mM BHB. As salt is a carrier, ketone salts have quite a high salt load (80+% RDA of sodium in a single serving) which triggers GI distress for some users. The BHB ketone ester raises ketones between 3-5 mM BHB. This is equivalent to 7-10 days of fasting worth of ketones. Diving one step further, if you look at the scientific literature, all the performance benefits of exogenous ketones were actually done by our research partners at the University of Oxford and NIH on our specific ketone ester in HVMN Ketone. In fact, emerging published data on ketone salts are showing that there's limited evidence for salts for athletic performance. In short, the evidence to date suggests that our ketone ester in HVMN Ketone is the real deal. Our Research Lead Dr. @BriannaStubbs recently published a paper investigating the kinetics of both salt and ester here if you'd like to see a formal whitepaper and discussion: https://www.frontiersin.org/arti...

@geoffreywoo lets! (seriously lets do this) 📊

@syswarren In my understanding, exogenous ketone supplements are shortcuts to raise the blood ketone levels without nutritional ketosis. That means that you can still eat carbs and get the benefits of ketones to some extent. (Source: Dom D'Agostino said it in a podcast.)

@syswarren yes, this is one of my personal favorite use cases! The transition into ketosis is tough because your brain and body has low glucose (from fasting or carb restriction) and has low ketones (ketone production has picked up yet). Drinking HVMN Ketone will bridge that gap of energy availability and make the transition into ketosis or a longer fast much more smoothly.

@geoffreywoo Awesome! Thank you!

@syswarren Yes, whilst taking ketone supplements doesn't help your body to make ketones, it will help to alleviate the nasty symptoms of ketone adaptation. Plus being a great source of energy for people who want more energy to work out whilst on a keto diet.

@syswarren Entering ketosis is not a challenge if you have adequate electrolytes. No headaches or side effects.

@hnshah thank you for the longtime support ! Excited to finally unveil this to the world. I’ll be online tomorrow morning with my team including our Research Lead Dr. @briannastubbs to answer any and all questions on the science, technology, and data.

@hnshah Thanks so much for the support!

@erickbarron86 I️ know and it’s part of the scaling operation of a novel process. We have a roadmap to scale this to be as cheap and accessible as possible: https://hvmn.com/blog/introducin...

@erickbarron86 Erick, you can take one bottle per day, but you certainly don't have to! HVMN Ketone is designed to be used "as needed" for the big days you need it.

@erickbarron86 @bdm_tastemakers would love to see a bit more info on dosage! The website says a single serving is 25 grams, thats $22-33 per serving! Whats a realistic dosage for the main use cases? Would you do a full 25g before every workout? To kick start a keto diet, would you just take full doses it for 3 days straight and then supplement with smaller amounts from there?

@dereklowe @datarade My responses on Twitter copied below: (1) Incorrect. HVMN Ketone is a food and has a nutrition label. Our partners at Oxford went through FDA GRAS process: https://www.accessdata.fda.gov/s... (2) The alcohol component is (R)-1,3 butanediol, a common food additive, which is rapidly converted into D-BHB. (3) Per your toxicity question, many kinetic and safety studies done on both animal and human subjects. Hence, FDA GRAS as a foodstuff. (4) Happy to discuss data and work in detail. Copying my colleague Dr. @BriannaStubbs, who ran a number of the human studies at Oxford.

@tvventythree that’s incorrect. You’re seeing exogenous ketones made of ketone salts or MCT oil. HVMN Ketone is a ketone ester, and it’s the world’s first ketone ester that’s FDA GRAS as a foodstuff (not a supplement). I️ actually taped a conversation with Prof. Dom D’agostino this past weekend about the first commercial availability of a ketone ester, and we’ll be posting that discussion later this week / next week.

@geoffreywoo Thats terrific news and reassuring. Thanks for following up and addressing concerns! Looking forward to the discussion with Dom.

@erickbarron86 yes, great fuel that helps smooth transition into endogenous ketosis

@erickbarron86 Great way to consume energy as ketones to help you make it through a fast without triggering insulin response

@geoffreywoo @briannastubbs @dtran320 Thanks David! Excited for you to try. Let's hit the trails again soon, that was a great 15mi run!

@geoffreywoo @bdm_tastemakers @dtran320 Thanks David, hope I can join you next time and be fueled by HVMN Ketone!

@beller @bdm_tastemakers did a tonne of hard work and I agree it looks great!

@paul_benigeri Insanely fun :)

@paul_benigeri I added you as a maker!