Probably the ultimate solution to implement a clean email signature easily.
I implemented WiseStamp within my organization and it allows me to change email signatures for all users and keep them synced. It also help my marketing activities - great product.
Really glitchy with Gmail, poor customer support, and lots of issues once I finally got it working.
I get asked about my email signature at least once per week - people think it's fantastic. My theory is that having my photo in my signature makes people more likely to respond to me because they see that I'm a real person, not just a random email address. I teach a lot of workshops on networking, and I highly encourage everyone to get their own WiseStamp signature to help direct potential new contacts toward the information online that they want to present. It helps control how people learn about you right off the bat, rather than having them rely on Googling you. It's one of my most-used tools in my arsenal.