Ollama has become a go-to for running LLMs locally thanks to its straightforward setup and “it just works” developer experience. The alternatives landscape spans everything from performance-tuned local runtimes like BaseRT (built to squeeze more throughput out of Apple Silicon), to infrastructure layers like liteLLM that unify and route requests across many providers (including local backends), to full app platforms like Dify that add workflows, RAG, and self-hosted LLMOps. On the hosted side, options like Groq Chat prioritize ultra-low latency and high throughput via an OpenAI-compatible API, while Replicate offers a managed, serverless-style way to run a wide catalog of models without standing up GPU infrastructure.
In evaluating these options, we looked at where inference runs (on-device vs cloud), speed and scalability, integration fit (OpenAI-compatible APIs, routing, observability), operational overhead (self-hosting vs managed), and how well each tool supports real-world product needs like workflows, compliance, and multi-model flexibility.