By far the best, lightest, and cheapest visual design tool.

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Ryan Hoover
@rrhoover · Founder, Product Hunt
Wow, that's a LONG product page. Well done though. Relevant: @liveink shared Sketch, a vector-based image editor a while back - http://www.producthunt.co/posts/162
M.G. Siegler
@mgsiegler · General Partner, GV
It's long been my go-to on OS X.
Kevin Li
@liveink · #NewStuff
pixelmator is legit as well
Steve Hannah
@shannah78 · Software Engineer, Codename One
A good, low-cost alternative to Photoshop. Interface is fairly intuitive, and performance seems pretty good. I'm a web and app developer that just needs to create custom header graphics with some text and images some times and Pixelmator works great for that.