Lise is an autonomous research engine. It reads the literature, forms hypotheses, runs the numbers, and returns a report where every claim is traceable to its evidence. Lise Meitner, 1878–1968, she explained nuclear fission. We named Lise after her.
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Maker
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Hey Product Hunt community 👋
For over 10 years I've worked across physics, chemistry, and math projects — from redox flow battery electrolytes to problems that had nothing to do with each other on the surface. But every single one had the same missing piece: I needed a research assistant, and I never had one.
Not just something to keep my notes organized. Someone who could go out, read the literature before I did, come back with a state-of-the-art report, help me see what's already been tried and what hasn't, and stay with me through the whole arc — from the first hypothesis to the paper I'd eventually have to write. Whether I was trying to design a new electrolyte chemistry, work through a math problem, or just needed one place where a research thread didn't get lost between browser tabs, notebooks, and PDFs — that assistant didn't exist. So I'd rebuild the same scaffolding myself, every time, for every new problem.
That's what Lise is.
It's named after Lise Meitner — one of the greatest physicists of the 20th century, who co-discovered nuclear fission and was written out of the Nobel Prize for it. We wanted to build something worthy of her name: a serious research partner, not a toy. Give it a question — a chemistry problem, a math conjecture, a literature gap you need mapped — and Lise plans the investigation, sweeps and reads the actual literature, builds and tests hypotheses, runs the analysis, and hands you back a real, citable report you can trust and build on.
Our bet is simple: every scientist on the planet should have access to the best research agents we know how to build — not just the ones with a lab's budget for RAs.
This is a first, real version, and I'd love your feedback — what you'd want it to do next, where it falls short, what "assistant" means for your field that we haven't thought of yet. I'll be in the comments all day.
— David
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Love the nod to Lise Meitner and the emphasis on traceable claims. One thing that would help a lot: let users upload their own PDFs or supplementary datasets and have Lise cross-reference those against its literature findings, so the reports blend published evidence with whatever internal notes or unpublished data you bring to the table.
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Maker
@aryaarkayaulwb you can do that! the base of this is that you have 5 running modes: quick, light and deep are for reference reading or dataset reading, like for instance gettin the state of the art on a question. Then Scientist and Program mode are fully autonomous research agents that take your data, your own findings and everyhting you add and perform your research goals. Program mode can take up to 24 hours of computing, going so deep that you can really adavance your research by months in hours.
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the traceability angle is genuinely cool, big fan of that. one thing i'd love is a way to export the underlying evidence graph as a structured file so i can drop it into zotero or share the reasoning chain with collaborators without screenshots. would make it way easier to cite or audit.
Report
Maker
@mirayj8ur will add that! Right now you can export everything, but will add a graph to make it easier with a direct zotero link.
Report
Love the Lise Meitner nod and the traceability angle is exactly what most AI research tools get wrong. One thing I'd love to see is a "confidence vs consensus" view for each claim, showing how strongly the cited sources agree and flagging anything where Lise is leaning on a single outlier paper. Would make the reports much easier to weigh when I'm cross-checking my own work.
Report
Gave it a spin on a tricky metabolism question and the traceable evidence trail was genuinely useful, saved me an hour of digging through PubMed. Love that it's named after Lise Meitner too.
Naming it after Lise Meitner is a really nice touch. Tested it on a niche biophysics question and the traceable citations in the report saved me at least an hour of digging.
Report
Love the idea behind the name and the traceable claims really do make it stand out from typical research tools. Tried it on a niche biotech question and the cited sources felt solid.
Love the nod to Lise Meitner and the emphasis on traceable claims. One thing that would help a lot: let users upload their own PDFs or supplementary datasets and have Lise cross-reference those against its literature findings, so the reports blend published evidence with whatever internal notes or unpublished data you bring to the table.
@aryaarkayaulwb you can do that! the base of this is that you have 5 running modes: quick, light and deep are for reference reading or dataset reading, like for instance gettin the state of the art on a question. Then Scientist and Program mode are fully autonomous research agents that take your data, your own findings and everyhting you add and perform your research goals. Program mode can take up to 24 hours of computing, going so deep that you can really adavance your research by months in hours.
the traceability angle is genuinely cool, big fan of that. one thing i'd love is a way to export the underlying evidence graph as a structured file so i can drop it into zotero or share the reasoning chain with collaborators without screenshots. would make it way easier to cite or audit.
@mirayj8ur will add that! Right now you can export everything, but will add a graph to make it easier with a direct zotero link.
Love the Lise Meitner nod and the traceability angle is exactly what most AI research tools get wrong. One thing I'd love to see is a "confidence vs consensus" view for each claim, showing how strongly the cited sources agree and flagging anything where Lise is leaning on a single outlier paper. Would make the reports much easier to weigh when I'm cross-checking my own work.
Gave it a spin on a tricky metabolism question and the traceable evidence trail was genuinely useful, saved me an hour of digging through PubMed. Love that it's named after Lise Meitner too.
@naimekini8upz thank you!
Naming it after Lise Meitner is a really nice touch. Tested it on a niche biophysics question and the traceable citations in the report saved me at least an hour of digging.
Love the idea behind the name and the traceable claims really do make it stand out from typical research tools. Tried it on a niche biotech question and the cited sources felt solid.