The Multiply Pill

Program a custom supplement pill for your health + energy.

9 followers

Program a custom supplement pill for your health + energy.

9 followers

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Launch tags:Health & Fitness•Productivity•3D Printer

Launch Team

Link Texting

I emailed multiple people working in the gut "space." There's 2 primary issues with this product that essentially make it vaporware tantamount to something like the Anat Baniel Therapy. * To time a release over various parts of the gut is too much of a challenge right now * Different folks have different motility

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10yr ago

The Multiply Pill

Maker

@datarade Thanks for your opinion, but we disagree! Our peer-reviewed data&papers prove that our technology works. For example, in this study we show that the release profiles of 3D printed capsules are remarkably consistent: http://www.sciencedirect.com/sci... While in this other study, we demonstrate the release/dissolution properties of 10 more 3D printed, FDA-approved pharmaceutical polymers: http://www.sciencedirect.com/sci... So, the tech is solid and the science is there to prove it. We know that the specific release time varies in the digestive system of every customer. That is where the power of 3D printing (=full customization) comes into play! If you feel like your pill releases your supplements (e.g. caffeine boost) too early or too late, we can modify its design and ship you a new version of the pill that is tailored to your needs (in other words, we can further delay or anticipate the release of the supplements). The end result of this iteration is a pill that is unique to you, because it was designed based on your specific feedback, which is determined by how your body works!

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10yr ago

The Multiply Pill

Maker

@datarade It's also important to add that the control of release time is one of the 3 unique features that we offer! The other 2 are the possibility to customize both the combination and the dosage of the supplements in a single, small pill. There is no other technology on the market that can offer any of these features!

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10yr ago

Link Texting

@fred_parietti I dont dispute that the technology for 3D printing can create a pill for pulsatile deployment. The problem with the technology is that simple time based release is not the only parameter to establish an effective delivery mechanism. As you know, for example - the FSVs depend on location in the GI tract for optimal absorption. You can try to time release into the duodenal-colonic axis, but the number of variables will render your methdology of iterating useless. As a company, you would argue that the timed release is an upgrade on the current supplements, but that only goes to support the relatively small need as absorption is fairly effective in the current paradigm. You could try to have everyone undergo a pill cam or Tc-99M Solid phase gastric emptying study, but also completely not feasible. If you throw in a touch of basic gastroenteritis or a transient intussception amongst a myriad of other fleeting conditions in the human gut, the timing of the release of your pill is rendered invalid. The technology needed to make timed or gated distribution effective would rely on more than just a 3D printed capsule form that yielded sustained releases.

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10yr ago

Link Texting

@fred_parietti @rrhoover @nivdror I hope PH comes up with a better process for all things supplements and big-school-credential touting.

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10yr ago

The Multiply Pill

Maker

@datarade Once again, we disagree with your posts. Luckily we got you to agree on the release capabilities of the 3D printed pills. You are not switching topics, and focusing on the absorption of the supplement. If you actually went on our website and used our pill customization interface, you would see that we put most supplements (vitamins, minerals) in the "release now" part of the capsule. In this respect, our pill behaves like a normal supplement pill, but with no eccipients and personalized combinations and quantities of supplements (unique features of our product).

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10yr ago

Growth Calculators

So interesting! Didn't know this was possible. Have you come across anyone who has health concerns or concerns about legitimacy around this? I know the drug and vitamin industry is pretty strict and somewhat controversial. I love the innovation, though!

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10yr ago

The Multiply Pill

Maker

@donte_ll certainly true about the controversy of the industry! Because of some of the negative publicity around supplements in general, we are doing everything we can to be transparent about our claims and the supplements we offer. Additionally, we are completely following the FDA's guidance on supplements to mitigate any safety concerns about our pill!

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10yr ago

Growth Calculators

@olbuckwilson Sounds good!

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10yr ago

So does this essentially create a pill with the required dose for the user? A bit confused of how the user gets the pill once they have received the correct dosage

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10yr ago

The Multiply Pill

Maker

@unofficialalai Yup, based on your basic information and goals, we recommend a pill with specific supplements and dosage. From there, we print and ship your pills to your doorstep!

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10yr ago

@tiffanyamykuo ah okay this sounds AMAZING!!! I would most definitely use it

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10yr ago

3D printing super pills? This just blows my mind. What really excites me about this though, is when 3D printers inevitably become a part of every household, people will be able to make their own pills.

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10yr ago

The Multiply Pill

Maker

@desmonddantzler Yes, it’s a very cool technology, at the intersection of robotics and pharma tech! However, we are not using standard, commercially available machines and materials. Trying something similar at home would not guarantee the same quality and reliability of our manufacturing facility. Our goal is to bring this technology to consumers in the simplest and fastest way. This way, they can personalize their pills online and then receive them right at their doorstep, without having to keep one more appliance in their homes!

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10yr ago

Link Texting

The number of Americans with any sort of actual vitamin deficiency is very low. This is hype central. Forgive me. I am more Maurice Hilleman and Derek Lowe than I am Ray Kurzweil. Nobody on their team has an organic chemistry background. The paper they got published had more to do with novel engineering than the chemistry of how the compounds reach the body. But I guess that's what happens when Elysium Health goes big off of MIT credentials, pupils see the same thing and pursue. I just emailed 100 organic chemists, more questions to come soon.

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10yr ago

The Multiply Pill

Maker

@datarade This comment is a little all over the place. In order: 1) The number of people with some sort of vitamin deficiency is surprisingly high, even in the US (one example: http://www.sciencedirect.com/sci...). We believe that a balanced diet can go a long way in ensuring the proper nutritional values. However, a large number of US customers would like to integrate their healthy diet with some particular combination of supplements in order to meed their nutrition goals (100% RDA). For these customers, we offer a completely personalized solution that gives them the supplements they need, in the quantities they need, without eccipients. This is light years ahead of the standard, mass-produced multivitamins that contain a generic combination of supplements in often eccessive quantities!

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10yr ago

The Multiply Pill

Maker

@datarade 2) Our CTO has a PhD in pharmaceutical technologies, and her publications won several international awards in the field (http://www.multiplylabs.com/#/te... ). THIS is the area where our technology comes from (pharma tech). The engineering/robotics part is the technology layer that makes it possible to bring this exciting discovery to the market. So you can avoid to bother those poor 100 organic chemists, and email instead some pharma experts. 3) We do not have any affiliation with Elysium. In fact, our approach is radically different. We do not pre-specify which supplements (and in which quantities) our customers should take. Moreover, we manufacture our pills (no contractors) because we have developed the first-ever manufacturing technology to produce personalized pills. Nobody else in the supplements (or pharma) fields can currently do the same.

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10yr ago

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@datarade I think you might be looking at this with a very severe filter. These guys are early but the core innovation seems to be a fairly fundamental one. The supplements market in the US is $40B a year and isn't really the most innovative market. I think this could move the meter.

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10yr ago

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@datarade I think you are applying too severe a filter on them. They are early but the innovation seems a very fundamental one in this space. Supplements is a large market, at $40B a year in the US alone. This potentially is disruptive in that market, as a start. That's not including any future roadmap into therapeutics.

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10yr ago

Interesting product. Why isn't there a "take before bed" option? Many people who experience nausea from supplements avoid it by taking them just before bed.

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10yr ago

The Multiply Pill

Maker

@kathchalmers You can certainty take your pill at night if you don't select the "energy" option! Because the supplements in the "energy" option is meant to keep you awake, we do not suggest to take pills containing energy prior to going to bed.

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10yr ago

San Diego Union-Tribune

This is awesome! It's like a sleep number mattress for my body's chemicals. I only got a 4 on AP Chem, but is there some sort of regiment of pills I could take to achieve a weight loss goal over a period of time? Or would the same pill taken every day but made of the right components help me achieve the same effect?

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10yr ago

The Multiply Pill

Maker

@justinboogaard If only weight loss was so easy! Our research shows that there is no specific supplement regimen for weight loss, as your supplement needs changes to support your exercise and other factors. But, you can easily change the supplements in your pill on a bi-weekly basis to match your supplement needs at that point in time.

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10yr ago

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